I "work" from home, in that I am writing up my PhD right now and can't be bothered to go into my office on campus every day, when I have mostly everything I need at home. However, I keep applying for temp jobs, because eventually sitting at home all by myself every day makes me a bit crazy...but I do keep in touch with other PhD writers via an online forum which is pretty active, so even though there isn't really anyone here, I talk to people online and make pacts to get things done, keep tabs on what other people are up to, and so on.
I'd love to start a decent freelance business someday, though. Editing and/or copywriting would be nice.