Far be it from me to be an expert at anything but having 4 CentOS VPS' perhaps maybe one relatively simple thing springs to mind:
CSF - ConfigServer Firewall, easy to install and can be configured through Webmin (if you use it).
It will also give a 'basic' indication of possible vulnerabilities, (eg. user/pass SSH server, unneeded services, etc).
Some of its functions
This suite of scripts provides:
Straight-forward SPI iptables firewall script
Daemon process that checks for login authentication failures for:
Courier imap, Dovecot, uw-imap, Kerio
openSSH
cPanel, WHM, Webmail (cPanel servers only)
Pure-ftpd, vsftpd, Proftpd
Password protected web pages (htpasswd)
Mod_security failures (v1 and v2)
Suhosin failures
Exim SMTP AUTH
Custom login failures with separate log file and regular expression matching
POP3/IMAP login tracking to enforce logins per hour
SSH login notification
SU login notification
Excessive connection blocking
UI Integration for cPanel, DirectAdmin and Webmin
Easy upgrade between versions from within cPanel/WHM, DirectAdmin or Webmin
Easy upgrade between versions from shell
Pre-configured to work on a cPanel server with all the standard cPanel ports open
Pre-configured to work on a DirectAdmin server with all the standard DirectAdmin ports open
Auto-configures the SSH port if it's non-standard on installation
Block traffic on unused server IP addresses - helps reduce the risk to your server
Alert when end-user scripts sending excessive emails per hour - for identifying spamming scripts
Suspicious process reporting - reports potential exploits running on the server
Excessive user processes reporting
Excessive user process usage reporting and optional termination
Suspicious file reporting - reports potential exploit files in /tmp and similar directories
Directory and file watching - reports if a watched directory or a file changes
Block traffic on the DShield Block List and the Spamhaus DROP List
BOGON packet protection
Pre-configured settings for Low, Medium or High firewall security (cPanel servers only)
Works with multiple ethernet devices
Server Security Check - Performs a basic security and settings check on the server (via cPanel/DirectAdmin/Webmin UI)
Allow Dynamic DNS IP addresses - always allow your IP address even if it changes whenever you connect to the internet
Alert sent if server load average remains high for a specified length of time
mod_security log reporting (if installed)
Email relay tracking - tracks all email sent through the server and issues alerts for excessive usage (cPanel servers only)
IDS (Intrusion Detection System) - the last line of detection alerts you to changes to system and application binaries
SYN Flood protection
Ping of death protection
Port Scan tracking and blocking
Permanent and Temporary (with TTL) IP blocking
Exploit checks
Account modification tracking - sends alerts if an account entry is modified, e.g. if the password is changed or the login shell
Shared syslog aware
Messenger Service - Allows you to redirect connection requests from blocked IP addresses to preconfigured text and html pages to inform the visitor that they have been blocked in the firewall. This can be particularly useful for those with a large user base and help process support requests more efficiently
Country Code blocking - Allows you to deny or allow access by ISO Country Code
Port Flooding Detection - Per IP, per Port connection flooding detection and mitigation to help block DOS attacks
DirectAdmin UI integration
Updated Webmin UI integration
WHM root access notification (cPanel servers only)
lfd Clustering - allows IP address blocks to be automatically propagated around a group of servers running lfd. It allows allows cluster-wide allows, removals and configuration changes
Quick start csf - deferred startup by lfd for servers with large block and/or allow lists
Distributed Login Failure Attack detection
Temporary IP allows (with TTL)
IPv6 Support with ip6tables
Integrated UI - no need for a separate Control Panel or Apache to use the csf configuration
Integrated support for cse within the Integrated UI
cPanel Reseller access to per reseller configurable options Unblock, Deny, Allow and Search IP address blocks
System Statistics - Basic graphs showing the performance of the server, e.g. Load Averages, CPU Usage, Memory Usage, etc
ipset support for large IP lists
...lots more!