Nxqd3051990, I assume you already have space and you are curious about advice on a set up?
I used to have a "daily" backup which would simply copy my important files from all over the place (in mydocuments, application settings, application's own directory, my own directories etc.) to one place on my local machine - that's more a backup from my stupidity deleting thing.
Then i would backup weekly automatically, sometimes more often manually, to a drive somewhere else
I would always put something automatic, I know I might forget if I don't. The challenge is maintaining the list as new applications add new folders, and I wish I remembered the piece of software i tried years ago that did a pretty good job at finding files to backup on its own...
But at the moment i dont backup online, just 2 usb drives, one which i take away on a rotation... online would be better but i always thought it'd be slow...