I just tried installing the latest GDS when it came out and was surprised to find that it worked with NOD32! It's great. Though I think GDS is a bit of an overkill.. I have it installed, but I find myself simply having no use for it.. I read newsfeeds in Thunderbird and I don't seem to have much of a need to search around for anything on my system because I already know exactly where everything is because I keep my system in order.
The scratch pad is kind of cool.. but then I use it far too rarely for it to be very useful to me. The system monitor is ok, but I can't say that I care too much about that kind of info. The news stuff only steals away even more of my time.. I already have about 20 blogs/newsfeeds to read every day.. not to mention forums and emails... it's quite the overload. The email checker is cool, but then I keep Thunderbird open almost always so I don't have much use for it...
To sum up, I don't see myself re enabling the autostart entry for GDS or even starting GDS anytime soon... what's your take? How do you use it?