I have nothing technical to contribute but, FWIW, I have it running. On my set-up it appears to affect none of Adobe CS, MS-Office 2007, WordPerfect, games, browsers, nor a host of other software. It might well be detrimental to the performance my system but I'm unaware of it, which is good enough for me.
(In case it's useful to know, Win 8.1-64, 12 GB RAM., Intel Core i7-980, SSDs) HTH.