Kaspersky is neat enough, and I certainly like the pro-active/behavioral blocking stuff that can catch stuff if it's (pretty good) heuristics fail. And their use of "has this file already been scanned?" database is great (after they went from NTFS streams to centralized databases), NOD32 doesn't have that (well, it keeps it in memory, but not on disk).
I still haven't decided whether to go for KAV or NOD at the museum; NOD is a bit faster and leaner, and slightly cheaper as well. I do NOT like their default adding "this message has been scanned" to incoming and outgoing emails, though; it's a false sense of security, and spoils anti-spam engines.