Portable version unpacked into its own directory works great.
ok so that's a big clue.
if i had to guess, i'd say the problem is that when you tried a reinstall you thought you deleted the old settings but they are still there.
one time there was an issue with a corrupt file in the PresetFormats directory. this problem can also happen if you copied files from one machine to another?
So here is my suggestion:
Delete the Program Files\Clipboard Help and Spell directory, AND delete the mydocuments ClipboardHelpAndSpell directory. You need to delete both.
Then reinstall CHS as normal.
If you have clip data you want to preserve, copy that someplace first.