So many times, after using many different USB drives (HDs, USB sticks...), windows gets all mixed up and starts assigning unusual letters to my drive, which makes backuping, errrrrr, an interesting experience.
Well, this depends on which software you are using for backup. I use SyncBackSE, and do not have to bother renaming USB device letters. This is because you can use your USB device's label name. Labels can be set once for all for a USB device very easily in Windows and other operating systems, I guess.
To refer to the USB device called my_device, you just use this instruction:
%LABEL=my_device%
To access to folder1 on your USB device, you just use this instruction
%LABEL=my_device%folder1\
No matter if the letter is G:\ of F:\ of K:\
You can also use serial numbers directly in your backup profiles. Details here:
http://www.2brightsparks....?action=kb&article=11