Just upgraded from Vista 32 to Win 7 x64. No issues with NOCLOSE on Vista 32.
On Win 7 x64, NOCLOSE seems to work interactively - meaning that you can focus a window and press the hot key to disable its close button, but you can't press the hot key to create a rule and have it persist.
This is a great utility. Is the problem Win 7 compatibility or going 64 bit? Any chance this incompatibility could be addressed?