I get my food safety info primarily from the Center for Science in the Public Interest (CSPI). They're an extremely skeptical outfit, and very much oriented toward consumer safeguards and truth in labeling.
This is clearly an area, like politics and religion, where people have wide differences of opinion.
http://www.cspinet.org/new/200502141.html
Today we're talking about Splenda, which contains the artificial sweetener sucralose. The product itself appears to be safe. Unlike sugar and high-fructose corn syrup, it is low in calories and does not promote tooth decay.
http://www.cspinet.org/reports/chemcuisine.htm
Approved in the United States in 1998, sucralose — marketed as Splenda — is used in soft drinks, baked goods, ice cream, sweetener packets, and other products. It previously had been used in Canada, Europe, and elsewhere. Sucralose is safer than saccharin, acesulfame-K, and cyclamate. The manufacturer, McNeil Nutritionals, advertises Splenda as being "made from sugar, so it tastes like sugar." That statement may be literally true, but is misleading. In fact, the sweetener is a synthetic chemical that is made by chemically reacting sugar (sucrose) with chlorine. However, just because it is synthetic does not mean it is unsafe.