So I just tried setting my 4k scale to 100%, and the software behaves normally(with no zooming, aka as expected).   The 4k screen is not my primary screen (see screencap above with the info), but when I set it back 125%, it goes back to the undesirable screen zooming behavior detailed in the video in above post.

My previous setup had monitors to below and to the right hand side of the 4k screen, could it be picking up on the last screen scaling value in some array/list somewhere? 

I just tried changing the organization to having the 4k screen on the left makes it behave normal even with screen scaling of the 4k monitor at 125%.  Working setup is below.

Yes, I've restarted many times. Here's  short video with a shot of all the screens while I try to Select A Region.  https://youtu.be/jlwzRozOK70

I download  a fresh portable build and it exhibited these same behavior.    It's so bizarre as It worked before the rearrangement change, but not after.

Organization by application exe name is nice, but I'd really like to add more context to the filename.  Is it possible to add the window title to the file naming patterns?  Ultimately it is to help name by the browser tab name, which seems to be passed along in window title. 

I'm looking at autohokey for inspiration