Power Desk...brings back a lot of memories for me. One of the first programs I geeked out on. Definitely my first alternative file browser.
First as in historical perceptive, perhaps. First, as in choice today: No way!
I used PowerDesk for many years, going back to Windows 95, when it was part of the Mijenix Fix-It Utilities package. After Ontrack bought Mijenix, the original developers formed a new company called Novatix and brought out a similar program called ExplorerPlus, which went nowhere. Ontrack did little development and eventually sold PowerDesk to VCOM, another software company that maintains orphan software without further development and sells it based on past reputation. It then passed on to Avanquest - same thing.
PowerDesk 6 was the last worthwhile version, but I haven't used it in nearly a decade.
My file manager of choice for the last 5 years has been XYplorer.