First: ghost and trueimage aren fine for disk imaging, but not really suitable for backups. Yes, trueimage does have a backup option, but it's not very good imho (I admin ~15 computers one place and purchased TI, and there's regularly problems... like backing up files that haven't changed since last incremental update, task scheduling problems, "weird things" if you cancel a backup etc.)
Anyway, stuff there is first backed up to a linux fileserver, and more-or-less daily, \\server\backup is copied to an external usb2 disk and put away in a burnproof safe (I still think it would be better taking it offsite, but oh well).
For private use, it's bothersome to be "fireproof". Either you need to take an usb disk (or dvd, if you don't have much data) and deposit it at a friend/bank/whatever - obviously it needs to be further away than just "next door". OR you can use one of the online services, but they cost $$$, and considering that most people have very poor upstream, this is only suitable for smaller amounts of data.
Personally, I don't even haven a backup scheme anymore >_<. Moved out on my own ~feb2006, before that I had backups to the server I have running at my mum's place. Haven't had time+money to set up a new server here; and I can't just use any old junk, it'll have to be quiet and power efficient as well as not be too large and ugly (*cough* girlfriend *cough*).